JPH0372080B

7 alpha -acylthio-15,16-methylene-3-oxo-17 alpha -pregna-1,4-diene-21,17-carbolactones of the formula wherein the 15,16-methylene group can be in the alpha - or beta - configuration, and R is a lower alkyl residue, have altialdosterone activity. They are prepared from corresponding DELTA -unsaturate...

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Hauptverfasser: KURAUSU NIKISHU, RUDORUFU UIIHIERUTO, DEIITAA BITORAA, UORUFUGANGU ROZERUTO, HENRII RAURENTO
Format: Patent
Sprache:eng
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Zusammenfassung:7 alpha -acylthio-15,16-methylene-3-oxo-17 alpha -pregna-1,4-diene-21,17-carbolactones of the formula wherein the 15,16-methylene group can be in the alpha - or beta - configuration, and R is a lower alkyl residue, have altialdosterone activity. They are prepared from corresponding DELTA -unsaturated compounds by chemical or microbiological 1,2-dehydrogenation.