6,11-DIHYDRO-5H-PYRIDO(2,13-B)(1,5) BENZODIAZEPINE-5-ONE AND -THION AND METHOD OF USING COMPOUND THEREOF FOR AIDS PREVENTION AND TREATMENT

6,11-DIHYDRO-5H-PYRIDO(2,13-B)(1,5) BENZODIAZEPINE-5-ONE AND -THION AND METHOD OF USING COMPOUND THEREOF FOR AIDS PREVENTION AND TREATMENT

Compound of formula wherein, Z is oxygen or sulfur; R is hydrogen, alkyl or fluoroalkyl, cyclopropyl, alkenyl or alkynyl, 2-halo-propen-1-yl, arylmethyl (wherein the aryl moiety is phenyl, thienyl or furanyl, alkanoyl, or alkoxyalkyl or alkylthioalkyl R is alkyl or fluoroalkyl, cycloalkyl, alkenyl o...

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Hauptverfasser: KAARU DEII HAAGUREIBU, BUORUFUHARUTO ENGERU, GIYUNTERU SHIYUMITSUTO, GIYUNTERU TORUMURITSUTSU, BUORUFUGANKU EEBERURAIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compound of formula wherein, Z is oxygen or sulfur; R is hydrogen, alkyl or fluoroalkyl, cyclopropyl, alkenyl or alkynyl, 2-halo-propen-1-yl, arylmethyl (wherein the aryl moiety is phenyl, thienyl or furanyl, alkanoyl, or alkoxyalkyl or alkylthioalkyl R is alkyl or fluoroalkyl, cycloalkyl, alkenyl or alkynyl, alkoxyalkyl or alkylthioalkyl, alkanoyl, hydroxyalkyl, arylmethyl (wherein the aryl moiety is phenyl, thienyl or furanyl), phenyl or alkoxycarbonylmethyl. These compounds, as well certain known 6, 11-dihydro-5H-pyrido[2,3-b][1,5]-benzodiazepin-5-ones are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection.