ANTI-ULCER AGENT

PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. CONSTITUTION:An anti-ulcer agent contains a compound of the formula [R1 is 2-COOH, 3-COOH, 4-C...

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Hauptverfasser: IKEDA TETSUYUKI, KAKEGAWA TOSHIO, SATO TOSHIO, NISHIKI MAYUMI, MATSUMOTO HITOSHI
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creator IKEDA TETSUYUKI
KAKEGAWA TOSHIO
SATO TOSHIO
NISHIKI MAYUMI
MATSUMOTO HITOSHI
description PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. CONSTITUTION:An anti-ulcer agent contains a compound of the formula [R1 is 2-COOH, 3-COOH, 4-COOH or 2-(5'-tetrazoyl); R2 is H, further NO2 when R1 is 2-COOH] as an active ingredient. The compound of the formula wherein R1 is 2-(5'-tetrazoyl) group has especially an excellent anti-ulcer activity and is prepared by condensing 4-hydroxy-2-methyl-3-methoxycarbonyl-2H-1,2- benzothiazine-1,1-dioxide with 2-(5'-tetrazoyl)-aniline.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTI-ULCER AGENT
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