ANTI-ULCER AGENT
PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. CONSTITUTION:An anti-ulcer agent contains a compound of the formula [R1 is 2-COOH, 3-COOH, 4-C...
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creator | IKEDA TETSUYUKI KAKEGAWA TOSHIO SATO TOSHIO NISHIKI MAYUMI MATSUMOTO HITOSHI |
description | PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. CONSTITUTION:An anti-ulcer agent contains a compound of the formula [R1 is 2-COOH, 3-COOH, 4-COOH or 2-(5'-tetrazoyl); R2 is H, further NO2 when R1 is 2-COOH] as an active ingredient. The compound of the formula wherein R1 is 2-(5'-tetrazoyl) group has especially an excellent anti-ulcer activity and is prepared by condensing 4-hydroxy-2-methyl-3-methoxycarbonyl-2H-1,2- benzothiazine-1,1-dioxide with 2-(5'-tetrazoyl)-aniline. |
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The compound of the formula wherein R1 is 2-(5'-tetrazoyl) group has especially an excellent anti-ulcer activity and is prepared by condensing 4-hydroxy-2-methyl-3-methoxycarbonyl-2H-1,2- benzothiazine-1,1-dioxide with 2-(5'-tetrazoyl)-aniline.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1991</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910111&DB=EPODOC&CC=JP&NR=H035425A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910111&DB=EPODOC&CC=JP&NR=H035425A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>IKEDA TETSUYUKI</creatorcontrib><creatorcontrib>KAKEGAWA TOSHIO</creatorcontrib><creatorcontrib>SATO TOSHIO</creatorcontrib><creatorcontrib>NISHIKI MAYUMI</creatorcontrib><creatorcontrib>MATSUMOTO HITOSHI</creatorcontrib><title>ANTI-ULCER AGENT</title><description>PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. 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The compound of the formula wherein R1 is 2-(5'-tetrazoyl) group has especially an excellent anti-ulcer activity and is prepared by condensing 4-hydroxy-2-methyl-3-methoxycarbonyl-2H-1,2- benzothiazine-1,1-dioxide with 2-(5'-tetrazoyl)-aniline.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBBw9Avx1A31cXYNUnB0d_UL4WFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8V4BHgbGpiZGpo7GhFUAAIxQHL4</recordid><startdate>19910111</startdate><enddate>19910111</enddate><creator>IKEDA TETSUYUKI</creator><creator>KAKEGAWA TOSHIO</creator><creator>SATO TOSHIO</creator><creator>NISHIKI MAYUMI</creator><creator>MATSUMOTO HITOSHI</creator><scope>EVB</scope></search><sort><creationdate>19910111</creationdate><title>ANTI-ULCER AGENT</title><author>IKEDA TETSUYUKI ; KAKEGAWA TOSHIO ; SATO TOSHIO ; NISHIKI MAYUMI ; MATSUMOTO HITOSHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH035425A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1991</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>IKEDA TETSUYUKI</creatorcontrib><creatorcontrib>KAKEGAWA TOSHIO</creatorcontrib><creatorcontrib>SATO TOSHIO</creatorcontrib><creatorcontrib>NISHIKI MAYUMI</creatorcontrib><creatorcontrib>MATSUMOTO HITOSHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IKEDA TETSUYUKI</au><au>KAKEGAWA TOSHIO</au><au>SATO TOSHIO</au><au>NISHIKI MAYUMI</au><au>MATSUMOTO HITOSHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTI-ULCER AGENT</title><date>1991-01-11</date><risdate>1991</risdate><abstract>PURPOSE:To provide an anti-ulcer agent having an excellent protective factor- promoting activity and extremely low toxicity by containing a specific thiazine-1,1-dioxide derivative as an active ingredient. CONSTITUTION:An anti-ulcer agent contains a compound of the formula [R1 is 2-COOH, 3-COOH, 4-COOH or 2-(5'-tetrazoyl); R2 is H, further NO2 when R1 is 2-COOH] as an active ingredient. The compound of the formula wherein R1 is 2-(5'-tetrazoyl) group has especially an excellent anti-ulcer activity and is prepared by condensing 4-hydroxy-2-methyl-3-methoxycarbonyl-2H-1,2- benzothiazine-1,1-dioxide with 2-(5'-tetrazoyl)-aniline.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | ANTI-ULCER AGENT |
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