JPH0325425B

Optically active and racemic 5- phenyl-1,3,4,5-tetrahydro-2H-1,4- benzodiazepin-2-one compounds of general formula (I> in which the centres of asymmetry in the 3- and 5-positions have the same absolute configuration [wherein R represents a hydrogen or halogen atom or a trifluoromethyl or nitro gr...

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Hauptverfasser: EBA PAROSHI, MAATON KAITAA, RASURO SUHORUNII, YURIANA REHIRIHITO, RAYOSU KISUFUARUDEI
Format: Patent
Sprache:eng
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Zusammenfassung:Optically active and racemic 5- phenyl-1,3,4,5-tetrahydro-2H-1,4- benzodiazepin-2-one compounds of general formula (I> in which the centres of asymmetry in the 3- and 5-positions have the same absolute configuration [wherein R represents a hydrogen or halogen atom or a trifluoromethyl or nitro group; R represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; R represents a group selected from those groups conventionally attached to the -CH(NH2)-COOH group of the optically active or racemic alpha - amino-acids; R represents a hydrogen atom or a chlorocarbonyl or carbamoyl group; and X represents a hydrogen or halogen atom or a trifluoromethyl group; with the proviso that if in the racemic compounds R represents a hydrogen atom then R represents other than an alkyl group having 1 to 6 carbon atoms] and acid addition salts thereof show enzyme inducing activity.