TRIAZOLYLHYDRAZIDE DERIVATIVE, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION HAVING SAID DERIVATIVE AS ACTIVE COMPONENT FOR TREATING ANGINA PECTORIS OR PREVENTING STOMACH ULCER AND PREPARATION THEREOF

This invention relates to novel triazolyl hydrazide derivatives and a process for the preparation thereof. The new triazolyl hydrazide derivatives of the general formula (I), wherein Q represents hydrogen or a heterocyclic group optionally substituted by a C1-4 alkyl group; or a group of the formula SR , wherein R stands for C1-4 alkyl or phenyl-(C1-4 alkyl), or a group of the formula NR R , wherein R and R each represent hydrogen, straight or branched chained C1-6 alkyl or C2-6 alkenyl; Z represents hydrogen or a group of the formula (C=X)-(N-R )-NR R , wherein X stands for oxygen or sulfur, R , R and R each stand for hydrogen or C1-4 alkyl; R denotes hydrogen, C1-4 alkyl or phenyl-(C1-4 alkyl) optionally substituted by one or more halogen atom(s), R stands for hydrogen or a group of the formula -(C=X)-(N-R )-NR R , wherein X, R , R and R are as stated above, with the proviso that if Z represents a group of the formula -(C=X)-(N-R )-NR R , R stands for hydrogen, and if Z represents hydrogen, R stands for a group of the formula (C=X)-(N-R )-NR R , and pharmaceutically acceptable acid addition salts thereof exert valuable antianginal and/or gastric ulcer inhibiting properties and are useful in therapy.