PYRIDE (2, 3-B) (1, 4) BENZOXAZEPINE (AND THIAZEPINE)-6 (5H)-ONE AND THION AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND FOR PREVENTING AND TREATING AIDS

NEW MATERIAL: A compound of formula I (X is O or S; Z is O or S; R is a 1-4C alkyl, 2-4C alkenyl, etc.; R is H, methyl, etc.; one of R and R is a 1-4C alkyl, a 1-2C aminoalkyl, etc., and the other is H, etc.; one of R to R is a 1-3C alkyl, hydroxyl, amino, etc., and one of the remaining three groups is H or methyl, and the remaining two groups are H, etc.). EXAMPLE: 2-Chloro-5-methylthiomethyl-pyrid[2,3-b][1,4]benzoxazepin-6(5H)one. USE: A medicine for preventing and treating AIDS, especially useful for infection of HIV-1 strain. PROCESS: A compound of formula I is obtained by changing a compound of formula II to a corresponding alkali or an alkaline earth metal compound of formula III, and further reacting the alkali or the alkaline earth metal compound of formula III with an alkylating agent of the formula R Y (Y is Cl, Br, an alkyl, etc.) or an acylating agent.