MONOCLONAL ANTIBODY AGAINST HUMAN INTERLEUKIN 6 RECEPTOR

PURPOSE:To produce an anti-human interleukin 6 receptor by cloning a cell line capable of recognizing human interleukin-6 receptor from a fused cell between a mammal immunized cell and a myeloma cell. CONSTITUTION:An immunized cell is collected from mammals by sensitizing mammals with human interleu...

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1. Verfasser: KISHIMOTO CHUZO
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To produce an anti-human interleukin 6 receptor by cloning a cell line capable of recognizing human interleukin-6 receptor from a fused cell between a mammal immunized cell and a myeloma cell. CONSTITUTION:An immunized cell is collected from mammals by sensitizing mammals with human interleukin-6 receptor antigen and the immunized cell is fused with a myeloma cell. Then a cell line capable of recognizing human interleukin-6 receptor is cloned from the fused cell to afford a hybridoma. Further, the hybridoma is cultured and a monoclonal antibody capable of recognizing the human interleukin-6 receptor is collected from the cultured mixture to provide the anti-human interleukin-6 receptor antibody.