METHOD AND DEVICE FOR AUTOMATICALLY GENERATING AND EVALUATING AGGLUTINATION REACTION IN ORDER TO MAINLY DETECTING SLIGHT AGGLUTINATION

PURPOSE: To enable automatically causing agglutination reaction for detecting minute agglutination by providing a centrifugal pipe in the direction parallel to the axis line of a centrifugal machine so that an optical concentration of mixture is continuously measured. CONSTITUTION: A reaction mixture comprising a suspended liquid and a blood serum is prepared, and the thermally insulated mixture is separated and shaken so that an agglutination degree is measured by an optical precipitation measurement method. The measurement is performed at a centrifugal pipe 2 of a centrifugal machine 1, and at that time, the centrifugal pipe 2 is provided in the direction parallel to the axis line of the centrifugal machine, so that an optical concentration of reaction mixture is continuously measured. When a change in optical concentration is found, a function of measurement data is examined for inflection. When an inflection takes plate, it is decided that no agglutination took place when a difference between a measurement curve and a specified reference curve (as shown with a doted line in the figure, specified as a permeability curve of straight line between a measurement start point and an inflection point) is significantly large. And, it is decided that no agglutination took place when a maximum deviation from the reference curve is at least a permeability T3%.