NOVEL ANTIBIOTIC SUBSTANCE YS-822A AND PRODUCTION THEREOF

NEW MATERIAL:The antibiotic substance YS-822 having the following properties. Appearance, pale yellow amorphous powder; melting point, 265 deg.C (decomposition); specific rotation, [alpha] =+16 (c=0.1, pyridine); elemental analysis (%), C 53.26-53.70, H 7.28-7.41, N 1.98-2.02; molecular formula, C37...

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Hauptverfasser:	ITO AKIRA, KOIDE YOSHIO, MIKI TOYOHIKO, IWAMOTO YUKIMASA, HASUDA KATSUMI, KUSUNOKI HARUO, IDO JUNKO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	NEW MATERIAL:The antibiotic substance YS-822 having the following properties. Appearance, pale yellow amorphous powder; melting point, 265 deg.C (decomposition); specific rotation, [alpha] =+16 (c=0.1, pyridine); elemental analysis (%), C 53.26-53.70, H 7.28-7.41, N 1.98-2.02; molecular formula, C37H59O14N; molecular weight, 741; color reactions, positive to Molish reaction and ninhydrin reaction, decoloring bromine and KMnO4 and negative to orcinol reaction and FeCl3 reaction; solubility, soluble in n-butanol, ethanol, methanol, dimethyl sulfoxide and pyridine, insoluble in benzene, ethyl acetate, chloroform, dichloromethane and acetone and scarcely soluble in water; etc. USE:Agent for inhibiting growth of yeast and fungi. PREPARATION:A bacterial strain belonging to genus Streptoverticillium [e.g., Streptoverticillium eurocidicus var. asterocidicus (FERM 2477)] is cultured.