PRODUCTION OF TISSUAL PLASMINOGEN ACTIVATOR

PURPOSE:To prevent peeling and death of cells from an adhesive carrier and enable continuation of production and culture of a tissual plasminogen activator(t-PA) for a long period by adding a special substance to a culture medium in culturing cells having the ability to produce the t-PA. CONSTITUTIO...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YOKOIKAWA KUMIO, AKIBA KIYOSHI, OMURA TAKEO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To prevent peeling and death of cells from an adhesive carrier and enable continuation of production and culture of a tissual plasminogen activator(t-PA) for a long period by adding a special substance to a culture medium in culturing cells having the ability to produce the t-PA. CONSTITUTION:Cells, derived from humans or animals and having the ability to produce the t-PA are cultured in a culture medium containing a meat extract derived from animals or fishes. The meat extract is obtained by concentrating meat water leached by dipping a lump of meat of animals or fishes in water. The amount thereof added is preferably 0.1-1.0%.