COMPOSITION FOR ORAL CAVITY APPLICATION

PURPOSE:To obtain the subject composition for oral cavity application capable of effectively suppressing the fixing of oral bacteria to the oral cavity and useful for the prevention of oral diseases such as gingivitis, alveolar pyorrhea and dental caries by compounding an egg, etc., obtained from poultry immunized with whole cell of oral cavity bacteria. CONSTITUTION:The whole cell or a cell component of oral bacteria such as Bacterioides gingivalis and Streptococcus mutans is used as an antigen. A poultry such as chicken, domestic duck or quail is immunized with the antigen or a combination of two or more kinds of the antigens together with an adjuvant by subcutaneous or intramuscular injection or oral administration together with feed or water. The egg, yolk or a water-soluble yolk fraction obtained from the immunized poultry is used as a component of the objective composition. The administration rate of the egg, etc., is preferably 0.0001-50g/kg/day. Since the antibody-containing component has excellent miscibility, the oral composition can be easily prepared without problem. The composition is used as toothpaste, wet dentifrice, mouth wash, oral pasta, etc.