METHOD FOR EXTRACTING ANTITUMOR SUBSTANCE

PURPOSE:To obtain an antitumor substance having stable and strong antitumor properties by extracting a crude drug by BAKU method with two kind of methods according to kind of the crude drug. CONSTITUTION:A crude drug selected from TENKISHI (semiaquilegiae redix), SOHGI, TETSUHAJU, SOUJISHI (Xanthii fructus), KUZETSUSOU, HOUBISOU (Dryopteris crassirhizomae rhizoma), YABUDOUTOU, TAKUSHITSU (root of Euphorbia Helioscopia L.), SUIYOUBAI, MOKKA (Chaenomelis fructus), SOUSHI, HOKOUEI (Taraxaci herba), KYUSEISHI (seed of Impatiens balsamica L.), BABOTSU (dried fruit body of Lasiosphaera nipponica Y.), RODORU (Euphorbiae pallasii radix), TOURIKON, RYOUKAOU, UDAIJU, NANSHOKUSHI, YOUTEIKON (root of Rumex japonicus Houtt.), KAGOSOU (Prunellae spica), HANPENREN (Lobeliae chinensis herba), MOKUFUYOU, SHUCHIN, HOKOKISHI, OUKASHA and BANRANKON (Baphicacanthis rhizoma et radix) is extracted with an acidic lower alcohol and shaken with n-butanol and them the butanol layer is collected to provide the active substance or a crude drug selected from JINKOTSUFU, KUBAKU (Dianthi herba), SEKISEN, NEKOBYOSOU, YOUTEIKON (root of Rumex japonicus Houtt.), KAGOSOU (Prunellae spica), HANPENREN (Lobeliae chinensis herba), MOKUFUYOU, SHOCHIN, HOKOKISHI, TOBANKI, SUIYOUBAI, MOKKA (Chaenomelis fructus), SOUSHI, HOROUEI (Taraxaci herba), KYUSEISHI (seed of Impatiens balsamica L.), BABOTSU (dried fruit body of Lasiosphaera nipponica Y.), SOUKASHA and OURANKON is extracted with a lower alcohol and extraction residue is extracted with hot water to provided the active substance.