JPH0235740B

JPH0235740B

Biphenylylpropionic acid derivatives of the formula: wherein R is an alkylcarbonyloxyalkyl group or an alkenylcarbonyloxyalkyl group having the formula: wherein R1 is a lower alkyl group having 1 to 5 carbon atoms and R2 is an alkyl group having 1 to 15 carbon atoms or an alkenyl group having 2 to 8...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MASUMOTO SHOZO, OKUMURA MAKOTO, UCHIDA KATSUHIRO, TONO MASAO, MIMURA MITSUO
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Biphenylylpropionic acid derivatives of the formula: wherein R is an alkylcarbonyloxyalkyl group or an alkenylcarbonyloxyalkyl group having the formula: wherein R1 is a lower alkyl group having 1 to 5 carbon atoms and R2 is an alkyl group having 1 to 15 carbon atoms or an alkenyl group having 2 to 8 carbon atoms, or a lactone having the formula: wherein R3 and R4 are hydrogen atom or a lower alkyl group having 1 to 2 carbon atoms, and n is an integer of 1 or 2. The compounds have excellent anti-inflammatory, analgesic and antipyretic activities. Moreover, the compounds have no irritation, rapid and long-acting, and high safety margin.