FUNCTIONAL POLYPEPTIDE
NEW MATERIAL:A functional peptide which is shown by formula I (C277 is 277 amino acid peptide residue corresponding to Pro -SER of cell adhesion domain of human fibronectin; H271 is 271 amino acid peptide residue correspond ing to Ala -Thr of heparin adhesion domain of human fibronectin; X is peptid...
Gespeichert in:
Hauptverfasser: | , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | NEW MATERIAL:A functional peptide which is shown by formula I (C277 is 277 amino acid peptide residue corresponding to Pro -SER of cell adhesion domain of human fibronectin; H271 is 271 amino acid peptide residue correspond ing to Ala -Thr of heparin adhesion domain of human fibronectin; X is peptide residue shown by formula II; (n) is 0 or 2) wherein the cell adhesion domain of human fibronectin is bonded directly or through a linker peptide to the heparin adhesion domain of human fibronectin. USE:A treating agent for wounds. PREPARATION:For example, a DNA to code a polypeptide wherein a cell adhe sion domain of human fibronectrin is bonded to a heparin adhesion domain of human fibronectin is synthesized, bonded to a manifestation vector to prepare a recombinant plasmid. The plasmid is introduced to a host cell, which is transformed and then the transformant is cultured to give a functional peptide shown by formula I. |
---|