ARYL- AND HETEROARYLETHANOL-PYRIDYLALKYLAMINE, PREPARATION THEREOF, USE THEREOF AS PROMOTING AGENT FOR PRODUCTION OF AND TREATING AGENT FOR CORPULENCY OF CATTLE
Novel aryl- and heteroarylethanolpyridylalkylamines of the formula I in which A stands for =CH- or =N-, R stands for hydrogen or methyl, R stands for hydrogen, hydroxyl, halogen, cyano, alkyl, haloalkyl, hydroxyalkyl, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, haloalkoxy,...
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Hauptverfasser: | , , , , |
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | Novel aryl- and heteroarylethanolpyridylalkylamines of the formula I
in which
A stands for =CH- or =N-,
R stands for hydrogen or methyl,
R stands for hydrogen, hydroxyl, halogen, cyano, alkyl, haloalkyl, hydroxyalkyl, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, haloalkoxy, haloalkylthio or NHSO2-alkyl,
R stands for hydrogen, hydroxyl, alkoxy or the radical -NR R ,
R stands for the radicals given under R ,
R stands for hydrogen, C1-C10-alkyl which is optionally substituted by hydroxyl, halogen, alkoxy, acyloxy or the radical -NR R , and also for the radical COR or the radical -O-Z-R ,
Z stands for C1-C10-alkylene, -alkenylene or alkynylene,
R represents hydrogen or alkyl,
R represents hydrogen, alkyl, haloalkyl or acyl, where R and R , together with the adjacent N atom, can form a saturated or unsaturated heterocyclic 4-, 5- or 6-membered ring,
R stands for hydrogen, optionally substituted alkyl or optionally substituted aryl,
R stands for the radicals indicated under R ,
R stands for hydroxyl, alkoxy or the radical -NR R ,
R stands for hydroxyl, alkoxy, acyloxy, optionally substituted aryloxy or aralkyloxy,
where in the pyridyl ring of the formula I the substituent R and the alkylamino group are in the p-position to one another,
and their physiologically tolerable salts and, if A stands for nitrogen, their N-oxides.
The present invention furthermore relates to processes for the preparation of the compounds, intermediates used in this process, and their use as performance promoters in animals and as anti-obesity agents. |
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