PRODUCTION OF ERYTHROFURANOSIL NUCLEOSIDE DERIVATIVE AND NOVEL DERIVATIVE

PURPOSE:To obtain the subject derivative useful for antiviral agent, etc., with simple method by affecting Lewis acid to specific protected oxetane cyclic compound. CONSTITUTION:A protected oxetane cyclic compound expressed by formula I (R1 and R2 are protecting group; Y is base) is reacted with Lew...

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Bibliographische Detailangaben
Hauptverfasser:	TAKITA TOMOHISA, MINAMI TAKAE, KATO KUNIMOTO, SHIMADA NOBUYOSHI, HASEGAWA SHIGERU, SAITO SEIICHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS DERIVATIVES THEREOF GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Beschreibung
Zusammenfassung:	PURPOSE:To obtain the subject derivative useful for antiviral agent, etc., with simple method by affecting Lewis acid to specific protected oxetane cyclic compound. CONSTITUTION:A protected oxetane cyclic compound expressed by formula I (R1 and R2 are protecting group; Y is base) is reacted with Lewis acid preferably in the copresence of base component contained in a nucleoside protecting functional group, removing protecting group as necessary, to afford the aimed compound expressed by formula II (R1' and R2' are H or protecting group). Besides, the compound expressed by formula III having H as groups R1' and R2' is a novel substance.