MEDICINE FOR TREATING HEART AND CIRCULATORY SYSTEM DISEASE, AND NOVEL PHENYLAMIDE

Drugs of the formula I in which R1, R2 and R3 can be identical or different and each can be a hydrogen atom, an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, halogen, nitro, amino, formyl, hydroxyl, mercapto, cyano group, a hydroxyl group substituted by an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, benzyl, pyridinyl, alkylsulphonyl, trifluoromethylsulphonyl, alkylcarbonyl, cyanoalkyl, hydroxyalkyl, dialkylaminoalkyl, aminocarbonylalkyl, dialkylaminocarbonylalkyl, N-cycloalkyl-N-alkylaminocarbonylalkyl, carboxyalkyl, alkoxycarbonylalkyl or alkoxyalkyl group, an amino group substituted by one or two alkylsulphonyl, trifluoromethylsulphonyl, alkylcarbonyl, formyl, aminocarbonyl, alkylaminocarbonyl or alkyl groups, a carbonyl group substituted by a hydroxyl, alkyl, alkoxy, amino, alkylamino or dialkylamino group, a sulphonyl group substituted by an amino, alkylamino, piperidino, morpholino or thiomorpholino group, or an alkylthio, alkylsulphinyl or alkylsulphonyl group, or in which two ortho substituents R2 and R3 form, together with the C atoms to which they are bonded, a five- or six-membered ring, X can be a bond, an alkylene group or, in the case where A is the carbonyl group -CO-, also the alkenylene group, and A and B are different and are the carbonyl group -CO- or the imino group -NH-, and R4 is a methyl, cyano, aminocarbonyl or aminomethyl group, R5 is a hydrogen atom or an alkyl group, R6 is an alkyl or cycloalkyl group, or R5 and R6 are, together with the C atom to which they are bonded, a cycloalkyl ring, the optically active forms thereof, the tautomers thereof and the physiologically tolerated salts thereof with inorganic and organic acids. The present invention also relates to phenylamides, process for the preparation of these compounds and the use thereof for preparing drugs, especially drugs acting to inhibit erythrocyte aggregation.