PRODUCTION OF 1,4-DIHYDROPYRIDINE DERIVATIVE

The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl)...

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Hauptverfasser: DAANIERU BOOSHINGU, RAASUROO REEBUAI, JIYURA MIKITE, JIYORUJI KOWAANIYUI, IRONA DEINIEESHIYU NEEE NAJII, EEBUA PEETSUIKU, IWAAN BETSUKU, EEBUA YUDEITO TAICHI NEEE YUHAASU, ISHIYUTOWAAN SHIMONIYUI, FURIJIESHIYU JIYORUGEENIYUI, PEETERU TENPE, EEBUA FURUDEIGA, KAARUMAAN NAJII, YAANOSHIYU IMURE, PAARU BENKOO, JIYORUJI ZARAWAARI, ERUZEEBETO KITSUSHIYUNEEE BERUTOOKU, ATSUTEIRA MAANDEI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl) methylene methanediamine with methyl acetoacetate in the presence of an amine compound or by reacting the monomeric or trimeric from of 2-nitrobenzaldimine with methyl acetoacetate.