FUNCTIONAL POLYPEPTIDE

NEW MATERIAL:The compound expressed by formula [A is fibronectin peptide residue having cell adhesion activity and selected from Ala -Gln (282 amino acid residues) and Ile -Gln (107 amino acid residues); B is fibrin- bonded domain peptide residue of fibronectin and is Asn -Glu (192 amino acid residu...

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Bibliographische Detailangaben
Hauptverfasser:	KIMIZUKA FUSAO, ODATE YOICHI, SUGAWARA YUKI, KATOU IKUNOSHIN, KINOSHITA RITSU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	NEW MATERIAL:The compound expressed by formula [A is fibronectin peptide residue having cell adhesion activity and selected from Ala -Gln (282 amino acid residues) and Ile -Gln (107 amino acid residues); B is fibrin- bonded domain peptide residue of fibronectin and is Asn -Glu (192 amino acid residues)], etc., and composed of a cell adhesion active polypeptide directly bonded with a fibrin-bonded active polypeptide. USE:A remedy for wound and a carrier for drug delivery system. PREPARATION:The functional polypeptide expressed by formula, etc., can be separated from a cultured product produced e.g., by linking a fragment containing a cDNA coding the cell-adhesion domain of fibronectin with a fragment containing a cDNA coding a fibrin-bonding domain, integrating into a plasmid, introducing the plasmid into a host cell and culturing the transformed cell.