NOVEL HIGH POLYMER POLYSACCHARIDE F-AB

PURPOSE:To efficiently produce high polymer polysaccharide F-Ab having penetrating and transferring effects, by cultivating a fungus belonging to the genus Fomes, capable of producing high polymer polysaccharide F-Ab and collecting high polymer polysaccharide F-Ab from the culture mixture. CONSTITUT...

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Bibliographische Detailangaben
Hauptverfasser: TAN MOTOMU, FUKUSHIMA ATSUSHI, MIKAMI YOICHI, AOKI MICHIKO, HIEDA TADAHARU
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To efficiently produce high polymer polysaccharide F-Ab having penetrating and transferring effects, by cultivating a fungus belonging to the genus Fomes, capable of producing high polymer polysaccharide F-Ab and collecting high polymer polysaccharide F-Ab from the culture mixture. CONSTITUTION:A fungus such as Fomes fomentarius IFO8426, IFO30371 or IFO30777 belonging to the genus Fomes, capable of producing high polymer polysaccharide F-Ab is cultivated in a medium consisting of glucose, Ebiosu(R), potassium phosphate, magnesium sulfate, etc. After the culture is over, a culture filtrate and a hot water extracted solution obtained by filtration are adsorbed on an ion exchanger, eluted, dialyzed and successively freeze-dried to give a freeze-dried high polymer polysaccharide F-Ab. The freeze-dried high polymer polysaccharide F-Ab is purified by gel filtration chromatography to give prepara tion of high polymer polysaccharide F-Ab.