NOVEL AMINOPYMELLIC ACID DERIVATIVE, ITS PRODUCTION AND USE THEREOF AS DRUG

Compounds of formula (I): in which U denotes a radical in which the dotted lines denote only one optional double bond of cis or trans configuration and a denotes a hydrogen atom, a methyl radical or a methylene group -CH2-, Y denotes a hydrogen atom or the residue of an amino acid bonded via the alp...

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Hauptverfasser: KONSUTANTAN AGUURIDA, PATORIKU FUOOBOO, SHIYANTARU DAME
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of formula (I): in which U denotes a radical in which the dotted lines denote only one optional double bond of cis or trans configuration and a denotes a hydrogen atom, a methyl radical or a methylene group -CH2-, Y denotes a hydrogen atom or the residue of an amino acid bonded via the alpha or omega carboxyl or of a peptide consisting of 2, 3 or 4 amino acids in which the amine is optionally acylated by an aliphatic acid or alkylated and R denotes a hydrogen atom or an optionally substituted alkyl radical, provided that if Y denotes a hydrogen atom, an alanine or proline radical and if a denotes a hydrogen atom, U contains a double bond, and their esters with alcohols, their primary and secondary amides and their salts with organic or inorganic acids or with bases. The compounds of formula (I) exhibit advantageous therapeutic properties which justify their use as medications.