5-PHENYL-1, 2, 3A, 4, 5, 9B-HEXAHYDRO-3H-BENZO (E) INDOLE, ITS PRODUCTION AND USE THEREOF AS MEDICINE

A 5-phenyl-1,3,3a,4,5,9b-hexahydro-3H-benz(e)indole compound of the formula I: I wherein R1 is hydrogen or C1-6 alkyl, R2 is hydrogen or C1-3 alkyl in the 3a- or 4-position, R3 and R4 are each hydrogen, hydroxyl, halogen, C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthio or trifluoromethyl, acetylamino or ami...

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Bibliographische Detailangaben
Hauptverfasser:	GERUTO SHIYUTAINAA, HARARUDO WAIFUENBATSUHA, HANSUUYURUGEN TETSUSHIENDORUFU, WARUTAA HIMUMERE, ERUNSUTO BUTSUSHIYUMAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A 5-phenyl-1,3,3a,4,5,9b-hexahydro-3H-benz(e)indole compound of the formula I: I wherein R1 is hydrogen or C1-6 alkyl, R2 is hydrogen or C1-3 alkyl in the 3a- or 4-position, R3 and R4 are each hydrogen, hydroxyl, halogen, C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthio or trifluoromethyl, acetylamino or amino and R5 is hydrogen or C1-3 alkyl, or a salt thereof with a physiologically tolerated acid. The compounds and compositions are useful for treating depression or trating convulsions and which exhibit a sedative and tranquilizing effect when administered to a patient.