JP2991832B

The invention relates to a novel process for the preparation of 5-hydroxy-3,4,5,6-tetrahydropyrimidine derivatives of the general formula (I) in which R represents optionally substituted alkyl, which is characterised in that amidines of the general formula (II) in which R has the abovementioned mean...

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Bibliographische Detailangaben
Hauptverfasser: HERUMAN ZAIFUERUTO, RAINHARUTO RANCHU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a novel process for the preparation of 5-hydroxy-3,4,5,6-tetrahydropyrimidine derivatives of the general formula (I) in which R represents optionally substituted alkyl, which is characterised in that amidines of the general formula (II) in which R has the abovementioned meaning, are reacted with epichlorohydrin of the formula (III) if appropriate in the presence of a diluent, at temperatures between 0 DEG C and 150 DEG C.