JP2939280B

NEW MATERIAL:Compounds shown by formula I to formula III {R is alkyl, alkenyl, phenyl which may be replaced, etc.; R is H or NH2; R F-substituted methoxy; R is alkyl, cycloalkyl, phenyl which may be replaced, etc.; X is group shown by formula IV (R is H, OH, NH2, aralkyl or alkyl which may be replac...

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Hauptverfasser:	KATSUBE TETSUTSUGU, FUJIWARA YOSHIMI, KIMURA TOMIO, INOE TERUHIKO, IWATA MASAYUKI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	KATSUBE TETSUTSUGU FUJIWARA YOSHIMI KIMURA TOMIO INOE TERUHIKO IWATA MASAYUKI
description	NEW MATERIAL:Compounds shown by formula I to formula III {R is alkyl, alkenyl, phenyl which may be replaced, etc.; R is H or NH2; R F-substituted methoxy; R is alkyl, cycloalkyl, phenyl which may be replaced, etc.; X is group shown by formula IV (R is H, OH, NH2, aralkyl or alkyl which may be replaced; R is H or alkyl which may be replaced; A is ethylene, trimethylene, etc.; m is 1 or 2), group shown by formula V [W is OH, alkoxy, etc.; R is H, OH, etc.; B is (CH2)1-4; n is 1 or 2], etc.; Y is 1-5C alkylene which may be replaced; Z is O or S}. EXAMPLE:6-Fluoro-8-difluoromethoxy-1-(4-fluorophenyl)-7-(1-piperazinyl )-1,4- dihydro-4-oxoquinolinecarboxylic acid. USE:An antimicrobial agent. PREPARATION:For example, a compound shown by formula VI is reacted with an amine compound shown by the formula X-H to give a compound shown by formula I.
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EXAMPLE:6-Fluoro-8-difluoromethoxy-1-(4-fluorophenyl)-7-(1-piperazinyl )-1,4- dihydro-4-oxoquinolinecarboxylic acid. USE:An antimicrobial agent. PREPARATION:For example, a compound shown by formula VI is reacted with an amine compound shown by the formula X-H to give a compound shown by formula I.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990825&DB=EPODOC&CC=JP&NR=2939280B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990825&DB=EPODOC&CC=JP&NR=2939280B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KATSUBE TETSUTSUGU</creatorcontrib><creatorcontrib>FUJIWARA YOSHIMI</creatorcontrib><creatorcontrib>KIMURA TOMIO</creatorcontrib><creatorcontrib>INOE TERUHIKO</creatorcontrib><creatorcontrib>IWATA MASAYUKI</creatorcontrib><title>JP2939280B</title><description>NEW MATERIAL:Compounds shown by formula I to formula III {R is alkyl, alkenyl, phenyl which may be replaced, etc.; R is H or NH2; R F-substituted methoxy; R is alkyl, cycloalkyl, phenyl which may be replaced, etc.; X is group shown by formula IV (R is H, OH, NH2, aralkyl or alkyl which may be replaced; R is H or alkyl which may be replaced; A is ethylene, trimethylene, etc.; m is 1 or 2), group shown by formula V [W is OH, alkoxy, etc.; R is H, OH, etc.; B is (CH2)1-4; n is 1 or 2], etc.; Y is 1-5C alkylene which may be replaced; Z is O or S}. 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	JP2939280B
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