JP2879395B

An anti-cancer composition comprising a rhodacyanine compound and cyclodextrin or derivative thereof, wherein said rhodacyanine compound is selected from the group consisting of compounds represented by the following Formula (I), the cation moiety of which has a log P value of 4.5-12: (I) wherein X1 and X2, which may be the same or different, each represents O, S, Se, Y1 represents O, S, Se, or R1 and R3, which may be the same or different, each represents an alkyl group; R2 represents an alkyl group, an aryl group or a heterocyclic group; Z1 and Z2, which may be the same or different, each represents an atomic group necessary to form a 5- or 6-membered ring; L1, L2 and L3, which may be the same or different, each represents a methine group or nitrogen atom and L1 and R3 may combine and form a 5- or 6-membered ring; R4 and R5, which may be the same or different, each represents an alkyl group; R6 and R7, which may be the same or different, each represents an alkyl group or an aryl group; Q represents a pharmaceutically acceptable anion; j and k, which may be the same or different, each represents 1 or 2; m and n, which may be the same or different, each represents 0 or 1.