JP2866134B

NEW MATERIAL:A functional peptide of formula I (C277 is a sequence of formula II exhibiting a 277 amino acid polypeptide residue corresponding to the Pro -Ser of the cell adhesion domain of human fibronectin; X is methionyl- alanine residue; (n) is 1, 0; EGF is a sequence of formula III exhibiting t...

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Hauptverfasser:	KAWASE YASUAKI, TAGUCHI YUKI, KIMIZUKA FUSAO, OODATE YOICHI, KATO IKUNOSHIN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	NEW MATERIAL:A functional peptide of formula I (C277 is a sequence of formula II exhibiting a 277 amino acid polypeptide residue corresponding to the Pro -Ser of the cell adhesion domain of human fibronectin; X is methionyl- alanine residue; (n) is 1, 0; EGF is a sequence of formula III exhibiting the amino acid residue of human epidermal growth factor). USE:A wound and ulcer curing agent having a cell adhesion activity and a cell growth acceleration activity. PREPARATION:For example, a DNA coding a polypeptide of formula II having the cell adhesion activity of human fibronectin(FN) and a polypeptide of formula III having the cell growth acceleration activity of human epidermal growth factor(FGF), respectively, are prepared and then combined with a suitable vector to form a recombined plasmid, which is inserted into a host such as Escherichia coli. The transformed host is cultured to prepare the polypeptide.