JP2787484B

NEW MATERIAL:A texture plasminogen-activating factor derivative losing amino acids 51-73. USE:Used as a therapeutic agent of thrombus. Has long half-life in blood and in vitro fibrinolytic property approximately equal to natural type. PREPARATION:At first, cDNA coding plasminogen-activating factor d...

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Bibliographische Detailangaben
Hauptverfasser: YAHARA HITOSHI, NAGAOKA TETSUYA, MATSUMOTO KEIJI, SUMYA TOORU
Format: Patent
Sprache:eng
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Zusammenfassung:NEW MATERIAL:A texture plasminogen-activating factor derivative losing amino acids 51-73. USE:Used as a therapeutic agent of thrombus. Has long half-life in blood and in vitro fibrinolytic property approximately equal to natural type. PREPARATION:At first, cDNA coding plasminogen-activating factor derivative having said amino acid sequence is synthesized and introduced into a manifestation vector. Next, an animal culturing cell is transformed by a manifestation vector containing said DNA sequence and the subject derivative is produced by the transformed cell.