JP2787098B

Chimeric monoclonal antibodies or fragments thereof are used for diagnostic assays for the quantitative immunological determination of substances in blood or serum from patients. For the diagnostic detection of substances in serum or blood from patients by binding of two monoclonal antibodies R1 and...

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Hauptverfasser: HERUMUUTO RENTSU, BURIGITSUTE KARUTSUA
Format: Patent
Sprache:eng
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Zusammenfassung:Chimeric monoclonal antibodies or fragments thereof are used for diagnostic assays for the quantitative immunological determination of substances in blood or serum from patients. For the diagnostic detection of substances in serum or blood from patients by binding of two monoclonal antibodies R1 and R2 which are directed against the substance, one antibody R1 of which is able to bind or is already bound to a solid phase, and the second antibody R2 carries a label, where appropriate binding of the antibody R1 to the solid phase, removal of the complex composed of R1, substance and R2, which has been formed and is bound to the solid phase, and detection via the labelling of the antibody R2, a chimeric monoclonal antibody or a fragment thereof is used at least as one of the antibodies R1 or R2.