JP2771494B
The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature...
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creator | BOKU JUYO KIN JUNKI JO TEISUN |
description | The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs. |
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A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.</description><edition>6</edition><language>eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; CARE OF BIRDS, FISHES, INSECTS ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NEW BREEDS OF ANIMALS ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR ; SPIRITS ; SUGARS ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980702&DB=EPODOC&CC=JP&NR=2771494B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980702&DB=EPODOC&CC=JP&NR=2771494B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BOKU JUYO</creatorcontrib><creatorcontrib>KIN JUNKI</creatorcontrib><creatorcontrib>JO TEISUN</creatorcontrib><title>JP2771494B</title><description>The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CARE OF BIRDS, FISHES, INSECTS</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NEW BREEDS OF ANIMALS</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>TRAPPING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZODyCjAyNzc0sTRx4mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8QgNTkbGxKgBACmCG38</recordid><startdate>19980702</startdate><enddate>19980702</enddate><creator>BOKU JUYO</creator><creator>KIN JUNKI</creator><creator>JO TEISUN</creator><scope>EVB</scope></search><sort><creationdate>19980702</creationdate><title>JP2771494B</title><author>BOKU JUYO ; KIN JUNKI ; JO TEISUN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2771494BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1998</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CARE OF BIRDS, FISHES, INSECTS</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NEW BREEDS OF ANIMALS</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>TRAPPING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BOKU JUYO</creatorcontrib><creatorcontrib>KIN JUNKI</creatorcontrib><creatorcontrib>JO TEISUN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BOKU JUYO</au><au>KIN JUNKI</au><au>JO TEISUN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>JP2771494B</title><date>1998-07-02</date><risdate>1998</risdate><abstract>The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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subjects | AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS SUGARS TRAPPING VINEGAR WINE |
title | JP2771494B |
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