JP2771494B

The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature...

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Hauptverfasser: BOKU JUYO, KIN JUNKI, JO TEISUN
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creator BOKU JUYO
KIN JUNKI
JO TEISUN
description The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.
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A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.</description><edition>6</edition><language>eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; CARE OF BIRDS, FISHES, INSECTS ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NEW BREEDS OF ANIMALS ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR ; SPIRITS ; SUGARS ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19980702&amp;DB=EPODOC&amp;CC=JP&amp;NR=2771494B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19980702&amp;DB=EPODOC&amp;CC=JP&amp;NR=2771494B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BOKU JUYO</creatorcontrib><creatorcontrib>KIN JUNKI</creatorcontrib><creatorcontrib>JO TEISUN</creatorcontrib><title>JP2771494B</title><description>The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. 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A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW BREEDS OF ANIMALS
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
SPIRITS
SUGARS
TRAPPING
VINEGAR
WINE
title JP2771494B
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