JP2771494B
The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature...
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Zusammenfassung: | The present invention relates to a transgenic nonhuman animal deficient in T-cells, which is provided by fusing heat shock protein (Hsp) gene with a promoter of a gene expressed in thymus and transferring it to an animal. A transgenic nonhuman animal with a shrunken thymus and a deficiency in mature T-cells can be obtained. This invention is useful for the fields of research of autoimmune disease genesis mechanisms, immune inhibitors and novel drugs. |
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