POLY-γ-GLUTAMIC ACID DERIVATIVE AND METHOD FOR MANUFACTURING THE SAME

To provide a poly-γ-glutamic acid derivative or its salt that improves solubility and viscosity of poly-γ-glutamic acid and has antibacterial properties.SOLUTION: Solubility and viscosity of poly-γ-glutamic acid can be improved by modifying a terminal amino group of poly-γ-glutamic acid and a second...

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Hauptverfasser: UMEYAMA AKINORI, IIZUKA MINAMI, NAGAI ATSUSHI
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide a poly-γ-glutamic acid derivative or its salt that improves solubility and viscosity of poly-γ-glutamic acid and has antibacterial properties.SOLUTION: Solubility and viscosity of poly-γ-glutamic acid can be improved by modifying a terminal amino group of poly-γ-glutamic acid and a secondary amine moiety of amide bond with a cationic functional group, thereby providing a quaternary ammonium adduct poly-γ-glutamic acid excellent in not only antibacterial properties but also texture.SELECTED DRAWING: None 【課題】ポリ-γ-グルタミン酸の溶解性や粘性を向上させ、抗菌性をもつポリ-γ-グルタミン酸誘導体またはその塩を提供する。【解決手段】ポリ-γ-グルタミン酸の末端アミノ基並びにアミド結合の二級アミン部位にカチオン性官能基を修飾することで、ポリ-γ-グルタミン酸の溶解性や粘度が向上し、抗菌性だけでなく感触にも優れる四級アンモニウム付加ポリ-γ-グルタミン酸を提供できる。【選択図】なし