EPHEDRA EXTRACT STRIPPED OF EPHEDRINE ALKALOIDS, METHOD FOR PRODUCING THE SAME AND USE OF THE SAME

To provide a method for producing an ephedra extract stripped of ephedrine alkaloids with high safety, by removing ephedrine alkaloids from ephedra extract while retaining some of the medicinal effects of ephedra, as well as an antineoplastic/antimetastatic agent, a pain inhibitor, and an anti-influ...

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Bibliographische Detailangaben
Hauptverfasser:	HYUGA SUMIKO, HYUGA SHOJI, AMAKURA YOSHIAKI, HANAWA TOSHIHIKO, YOSHIMURA MORIO, YAMASHITA TADATOSHI, AIDA YUKIHIRO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	To provide a method for producing an ephedra extract stripped of ephedrine alkaloids with high safety, by removing ephedrine alkaloids from ephedra extract while retaining some of the medicinal effects of ephedra, as well as an antineoplastic/antimetastatic agent, a pain inhibitor, and an anti-influenza virus drug that include the ephedra extract as an active ingredient.SOLUTION: A production method includes removing ephedrine and pseudoephedrine from hot water extract and/or dried extract from ephedra, through cation exchange chromatography.SELECTED DRAWING: None 【課題】麻黄の有するいくつかの薬効を保持したまま麻黄エキスからエフェドリンアルカロイドを除去することにより、安全性の高いエフェドリンアルカロイド除去麻黄エキスを製造するための方法、並びにそれを有効成分とする抗がん・抗転移薬、疼痛抑制薬及び抗インフルエンザウイルス薬を提供する。【解決手段】麻黄の熱水抽出液および／または熱水抽出物から陽イオン交換クロマトグラフィーによりエフェドリンとプソイドエフェドリンを除去することを特徴とする製造方法である。【選択図】なし