COMPOSITIONS AND METHODS FOR INHIBITING BIOLOGICAL ACTIVITY OF SOLUBLE BIOMOLECULES

To provide methods and compositions based on alternative approaches for harnessing a subject's own immune system against cancer, including weakening of the tumor's defensive system.SOLUTION: A particle has at least one surface and an agent immobilized on the surface, wherein the agent sele...

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Bibliographische Detailangaben
1. Verfasser: LOUIS HAWTHORNE
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide methods and compositions based on alternative approaches for harnessing a subject's own immune system against cancer, including weakening of the tumor's defensive system.SOLUTION: A particle has at least one surface and an agent immobilized on the surface, wherein the agent selectively binds to a target that is a first member of a specific binding pair; and binding of the target to the particle inhibits the interaction of the target with a second member of the specific binding pair.SELECTED DRAWING: Figure 2 【課題】腫瘍の防御システムを弱めることを含む、がんに対する対象自身の免疫系を利用するための代替的なアプローチに基づく方法及び組成物を提供する。【解決手段】少なくとも1つの表面及び前記表面に固定された薬剤を有する粒子であって、前記薬剤は、特異的結合ペアの第1のメンバーである標的と選択的に結合し、前記標的の前記粒子との結合は、前記標的と前記特異的結合ペアの第2のメンバーとの相互作用を阻害する、粒子である。【選択図】図2