METHODS FOR ANALYSIS OF CIRCULATING CELLS

To provide methods for characterizing and analyzing circulating cells, in particular, to provide methods for confirming the identity of an individual cell and confirming that the obtained sample is derived from a single cell of a defined identity.SOLUTION: Additional methods are provided for analyzi...

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Bibliographische Detailangaben
Hauptverfasser:	ELIZABETH RIVERS, MAXIM BREVNOV
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide methods for characterizing and analyzing circulating cells, in particular, to provide methods for confirming the identity of an individual cell and confirming that the obtained sample is derived from a single cell of a defined identity.SOLUTION: Additional methods are provided for analyzing a single cell sample to determine copy number variation and aneuploidy in the context of circulating fetal cells, microdeletions, single nucleic acid variations associated with cancer, or early relapse of cancer and metastasis.SELECTED DRAWING: Figure 1 【課題】本発明は、循環細胞を特徴解析および分析するための方法を提供する。特に本発明は、個々の細胞の固有性を確認する方法、および取得されたサンプルが、既定された固有性の一つの細胞に由来することを確認する方法を提供する。【解決手段】循環胎児細胞、微小欠失、癌に関連する一塩基変動、または癌の早期再発と転移の状況において、コピー数変動および異数性を決定するために一つの細胞のサンプルを分析する追加の方法が提供される。【選択図】図１