BLONANSERIN-CONTAINING PATCH

To provide a patch containing blonanserin and a rubber-based adhesive base, ensuring superior skin penetrability of blonanserin.SOLUTION: A patch includes an adhesive layer on a support. The adhesive layer includes blonanserin or a pharmaceutically acceptable salt thereof, a rubber-based adhesive ba...

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Bibliographische Detailangaben
Hauptverfasser:	UCHIDA HISASHI, TAKAMI ATSUO, AMANO SATOSHI, KOMATSUZAKI CHIHIRO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a patch containing blonanserin and a rubber-based adhesive base, ensuring superior skin penetrability of blonanserin.SOLUTION: A patch includes an adhesive layer on a support. The adhesive layer includes blonanserin or a pharmaceutically acceptable salt thereof, a rubber-based adhesive base, acetic acid, acetate, and liquid paraffin. In the adhesive layer, the value calculated by the formula: {acetic acid content (mass%)×acetate content (mass%)}/blonanserin content (mass%) is 0.02-30.SELECTED DRAWING: None 【課題】ブロナンセリンの皮膚透過性に優れる、ブロナンセリン及びゴム系粘着基剤を含有する貼付剤の提供。【解決手段】支持体上に粘着剤層を備える貼付剤であって、上記粘着剤層が、ブロナンセリン又はその薬学的に許容可能な塩と、ゴム系粘着基剤と、酢酸と、酢酸塩と、流動パラフィンと、を含有し、上記粘着剤層において下記式：｛酢酸の含有量（質量％）×酢酸塩の含有量（質量％）｝／ブロナンセリンの含有量（質量％）で算出される値が０．０２～３０である、貼付剤。【選択図】なし