ANTI-FLT-1 ANTIBODIES FOR TREATING DUCHENNE MUSCULAR DYSTROPHY

To provide anti-FLT-1 antibodies in the treatment of Duchenne muscular dystrophy.SOLUTION: The present invention provides, among other things, anti-Flt-1 antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according...

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Hauptverfasser: HANS DE HAARD, SOFIE GABRIELS, DENNIS KEEFE, NATALIE DE JONGE
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creator HANS DE HAARD
SOFIE GABRIELS
DENNIS KEEFE
NATALIE DE JONGE
description To provide anti-FLT-1 antibodies in the treatment of Duchenne muscular dystrophy.SOLUTION: The present invention provides, among other things, anti-Flt-1 antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-1 antibody or antigen-binding protein thereof so as to reduce intensity, severity, or frequency of at least one symptom or feature of DMD, or to delay DMD onset.SELECTED DRAWING: None 【課題】デュシェンヌ型筋ジストロフィーの治療における抗FLT-1抗体の提供。【解決手段】本発明はとりわけ、筋ジストロフィー、特にデュシェンヌ型筋ジストロフィー(DMD)を治療するための抗Flt-1抗体及び方法を提供する。いくつかの実施形態において、本発明による方法は、DMDの少なくとも1つの症状または特徴が強度、重症度もしくは頻度において減少するように、またはその発症が遅延するように、DMDを患っているまたはそれを患いやすい個体に、抗Flt-1抗体またはその抗原結合タンパク質の治療に有効な量を投与することを含む。【選択図】なし
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title ANTI-FLT-1 ANTIBODIES FOR TREATING DUCHENNE MUSCULAR DYSTROPHY
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