MAGNETIC MICROSCOPE

To provide a magnetic microscope tha t can observe vitality of individual cells.SOLUTION: In a magnetic microscope 61, conventional GSR sensors are downsized, and precisely arranged on a magnetic sensor element grid substrate to fabricate a magnetic sensor grid, the grid is arranged under Petri dish...

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Hauptverfasser:	MOTOKURA YOSHINOBU, MOTOKURA SHIMPEI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY MEASURING MEASURING ELECTRIC VARIABLES MEASURING MAGNETIC VARIABLES METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide a magnetic microscope tha t can observe vitality of individual cells.SOLUTION: In a magnetic microscope 61, conventional GSR sensors are downsized, and precisely arranged on a magnetic sensor element grid substrate to fabricate a magnetic sensor grid, the grid is arranged under Petri dish 62 during cell observation, a magnetic field generated from a cell is measured, and distribution of current elements flowing in the cell is calculated, which can be displayed in a PC image as an image figure. Combining the magnetic microscope and an optical microscope 64 makes it possible to easily observe a mechanical motion and movement of a shape change of cells and the degree of activation of each cell in real-time.SELECTED DRAWING: Figure 8 【課題】個々の細胞の活力を観察できる磁気顕微鏡を提供する。【解決手段】本発明は、従来のＧＳＲセンサをより小型化して、磁気センサ素子グリッド基板に緻密に配置して、磁気センサグリッドを作製して、それを細胞観察時のシャーレ６２の下に配置して、細胞が発する磁界を計測し、細胞内に流れる電流素片分布を計算し、それをＰＣ画像にイメージ図として表示することを可能にした磁気顕微鏡６１である。この磁気顕微鏡と光学顕微鏡６４を組み合わせることで、リアルタイムで細胞の機械的運動と形状変化の動きと各細胞の活性化度を容易に観察できるようにすることができる。【選択図】図８