DEACETOXY CEPHALOSPORIN C-PRODUCING BACTERIAL STRAIN FOR 7-ADCA PRODUCTION WITH HIGH CONCENTRATION AND HIGH PURITY, AND PRODUCTION METHOD USING THE SAME
To develop a bacterial strain that can produce the target substance DAOC at high purity with productivity increased for deacetoxy cephalosporin C (DAOC) and decreased for byproducts.SOLUTION: Disclosed herein are a bacterial strain with excellent deacetoxy cephalosporin C (DAOC) productivity and a u...
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Zusammenfassung: | To develop a bacterial strain that can produce the target substance DAOC at high purity with productivity increased for deacetoxy cephalosporin C (DAOC) and decreased for byproducts.SOLUTION: Disclosed herein are a bacterial strain with excellent deacetoxy cephalosporin C (DAOC) productivity and a use thereof. A mutant bacterial strain with improved DAOC productivity and a use thereof for producing 7-amino deacetoxy cephalosporanic acid (7-ADCA) are provided.SELECTED DRAWING: Figure 4
【課題】デアセトキシセファロスポリンC(Deacetoxy cephalosporin C;DAOC)生産性を高め、副産物の生産性を低めることで、目的物質であるDAOCの純度が高い生産菌株の開発。【解決手段】デアセトキシセファロスポリンC(Deacetoxy cephalosporin C;DAOC)生産能に優れた菌株およびその用途に関するものであって、改善されたDAOC生産能を有する変異菌株およびその7-ADCA(7-Amino deacetoxy cephalosporanic acid)の製造のための用途が提供される。【選択図】図4 |
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