METHOD FOR ASSISTING DETECTION OF HEPATOMA
To provide a method for assisting detection of hepatoma with which hepatoma can be detected with higher sensitivity than a known method.SOLUTION: A method for assisting detection of hepatoma includes measuring full-length glypican-3 in a blood specimen separated from a living body, and measuring gly...
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| creator | NISHII TOMONORI YAGI SHINTARO AOYANAGI KATSUMI NOJIMA HISASHI |
| description | To provide a method for assisting detection of hepatoma with which hepatoma can be detected with higher sensitivity than a known method.SOLUTION: A method for assisting detection of hepatoma includes measuring full-length glypican-3 in a blood specimen separated from a living body, and measuring glypican-3 having an N-terminus sub-unit. The method includes taking the ratio of a measured value of the full-length glypican-3 to a measured value of the glypican-3 having an N-terminus sub-unit (measured value of full-length glypican-3/measured value of glypican-3 having N-terminus sub-unit), and the ratio higher than that of an able-bodied person indicates the possibility that the living body has hepatoma.SELECTED DRAWING: Figure 1
【課題】公知の方法よりも高感度に肝細胞がんを検出することが可能な、肝細胞がんの検出を補助する方法を提供すること。【解決手段】肝細胞がんの検出を補助する方法は、生体から分離された血液検体中の全長グリピカン－３を測定することと、Ｎ末端側サブユニットを有するグリピカン－３を測定することとを含む。全長グリピカン－３の測定値とＮ末端側サブユニットを有するグリピカン－３の測定値との比（全長グリピカン－３の測定値／Ｎ末端側サブユニットを有するグリピカン－３の測定値）が、健常者よりも高いことが、生体が肝細胞がんに罹患している可能性が高いことを示す。【選択図】図１ |
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【課題】公知の方法よりも高感度に肝細胞がんを検出することが可能な、肝細胞がんの検出を補助する方法を提供すること。【解決手段】肝細胞がんの検出を補助する方法は、生体から分離された血液検体中の全長グリピカン－３を測定することと、Ｎ末端側サブユニットを有するグリピカン－３を測定することとを含む。全長グリピカン－３の測定値とＮ末端側サブユニットを有するグリピカン－３の測定値との比（全長グリピカン－３の測定値／Ｎ末端側サブユニットを有するグリピカン－３の測定値）が、健常者よりも高いことが、生体が肝細胞がんに罹患している可能性が高いことを示す。【選択図】図１</description><language>eng ; jpn</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240430&DB=EPODOC&CC=JP&NR=2024058961A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240430&DB=EPODOC&CC=JP&NR=2024058961A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NISHII TOMONORI</creatorcontrib><creatorcontrib>YAGI SHINTARO</creatorcontrib><creatorcontrib>AOYANAGI KATSUMI</creatorcontrib><creatorcontrib>NOJIMA HISASHI</creatorcontrib><title>METHOD FOR ASSISTING DETECTION OF HEPATOMA</title><description>To provide a method for assisting detection of hepatoma with which hepatoma can be detected with higher sensitivity than a known method.SOLUTION: A method for assisting detection of hepatoma includes measuring full-length glypican-3 in a blood specimen separated from a living body, and measuring glypican-3 having an N-terminus sub-unit. The method includes taking the ratio of a measured value of the full-length glypican-3 to a measured value of the glypican-3 having an N-terminus sub-unit (measured value of full-length glypican-3/measured value of glypican-3 having N-terminus sub-unit), and the ratio higher than that of an able-bodied person indicates the possibility that the living body has hepatoma.SELECTED DRAWING: Figure 1
【課題】公知の方法よりも高感度に肝細胞がんを検出することが可能な、肝細胞がんの検出を補助する方法を提供すること。【解決手段】肝細胞がんの検出を補助する方法は、生体から分離された血液検体中の全長グリピカン－３を測定することと、Ｎ末端側サブユニットを有するグリピカン－３を測定することとを含む。全長グリピカン－３の測定値とＮ末端側サブユニットを有するグリピカン－３の測定値との比（全長グリピカン－３の測定値／Ｎ末端側サブユニットを有するグリピカン－３の測定値）が、健常者よりも高いことが、生体が肝細胞がんに罹患している可能性が高いことを示す。【選択図】図１</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDydQ3x8HdRcPMPUnAMDvYMDvH0c1dwcQ1xdQ7x9PdT8HdT8HANcAzx93XkYWBNS8wpTuWF0twMSm6uIc4euqkF-fGpxQWJyal5qSXxXgFGBkYmBqYWlmaGjsZEKQIAkyMlDw</recordid><startdate>20240430</startdate><enddate>20240430</enddate><creator>NISHII TOMONORI</creator><creator>YAGI SHINTARO</creator><creator>AOYANAGI KATSUMI</creator><creator>NOJIMA HISASHI</creator><scope>EVB</scope></search><sort><creationdate>20240430</creationdate><title>METHOD FOR ASSISTING DETECTION OF HEPATOMA</title><author>NISHII TOMONORI ; YAGI SHINTARO ; AOYANAGI KATSUMI ; NOJIMA HISASHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2024058961A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2024</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>NISHII TOMONORI</creatorcontrib><creatorcontrib>YAGI SHINTARO</creatorcontrib><creatorcontrib>AOYANAGI KATSUMI</creatorcontrib><creatorcontrib>NOJIMA HISASHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NISHII TOMONORI</au><au>YAGI SHINTARO</au><au>AOYANAGI KATSUMI</au><au>NOJIMA HISASHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR ASSISTING DETECTION OF HEPATOMA</title><date>2024-04-30</date><risdate>2024</risdate><abstract>To provide a method for assisting detection of hepatoma with which hepatoma can be detected with higher sensitivity than a known method.SOLUTION: A method for assisting detection of hepatoma includes measuring full-length glypican-3 in a blood specimen separated from a living body, and measuring glypican-3 having an N-terminus sub-unit. The method includes taking the ratio of a measured value of the full-length glypican-3 to a measured value of the glypican-3 having an N-terminus sub-unit (measured value of full-length glypican-3/measured value of glypican-3 having N-terminus sub-unit), and the ratio higher than that of an able-bodied person indicates the possibility that the living body has hepatoma.SELECTED DRAWING: Figure 1
【課題】公知の方法よりも高感度に肝細胞がんを検出することが可能な、肝細胞がんの検出を補助する方法を提供すること。【解決手段】肝細胞がんの検出を補助する方法は、生体から分離された血液検体中の全長グリピカン－３を測定することと、Ｎ末端側サブユニットを有するグリピカン－３を測定することとを含む。全長グリピカン－３の測定値とＮ末端側サブユニットを有するグリピカン－３の測定値との比（全長グリピカン－３の測定値／Ｎ末端側サブユニットを有するグリピカン－３の測定値）が、健常者よりも高いことが、生体が肝細胞がんに罹患している可能性が高いことを示す。【選択図】図１</abstract><oa>free_for_read</oa></addata></record> |
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| title | METHOD FOR ASSISTING DETECTION OF HEPATOMA |
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