COMPOSITION FOR IMPROVING MITOCHONDRIAL ACTIVITY

To provide a new material derived from a natural product effective for mitochondrial activation or the like.SOLUTION: Provided is a food composition or a pharmaceutical composition containing any of chlorogenic acid, for improving mitochondrial activity. The chlorogenic acids are preferably any sele...

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Bibliographische Detailangaben
Hauptverfasser:	ARAI YOSHINOBU, IWATA KENGO, ISODA HIROKO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	To provide a new material derived from a natural product effective for mitochondrial activation or the like.SOLUTION: Provided is a food composition or a pharmaceutical composition containing any of chlorogenic acid, for improving mitochondrial activity. The chlorogenic acids are preferably any selected from a group consisting of 3-o-caffeoylquinic acid, 5-o-caffeoylquinic acid, and isoorientin. The composition is useful for treatment of any selected from a group consisting of diseases characterized by morphological maturation failure of astrocytes, including Alexander disease; non-disease metabolic disorders including deterioration of sugar and lipid metabolism associated with aging; metabolic diseases including diabetes, high blood pressure, dyslipidemia, fatty liver, metabolic syndrome and obesity; and sarcopenia caused by aging or the metabolic disorders.SELECTED DRAWING: Figure 1 【課題】ミトコンドリア活性化等に有効な天然物に由来する新規素材を提供する。【解決手段】クロロゲン酸類のいずれかを含む、ミトコンドリア活性向上用の、食品組成物又は医薬組成物を提供する。クロロゲン酸類は、3-o-カフェオイルキナ酸、5-o-カフェオイルキナ酸、及びイソオリエンチン、からなる群から選択されるいずれかであることが好ましい。本発明の組成物は、アレキサンダー病を含む、アストロサイトの形態的成熟不全を特徴とする疾患；加齢に伴う糖及び脂質代謝の低下を含む、非疾患性の代謝障害；糖尿病、高血圧、脂質異常症、脂肪肝、メタボリックシンドローム、肥満症を含む、代謝性疾患；及び加齢又は前記代謝障害に起因する筋肉減少症（サルコペニア）からなる群より選択されるいずれかの処置のために有用である。【選択図】図１