THIADIAZINE DERIVATIVES

To provide modulators of α7 nicotinic acetylcholine receptor activity.SOLUTION: The present invention provides a compound of formula (I) or its pharmaceutically acceptable salt thereof, biologically active metabolite, prodrug, racemate, enantiomer, diastereomer, solvate, or hydrate. Specifically, 5-...

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Bibliographische Detailangaben
Hauptverfasser:	PAL TAPOLCSANYI, ESRTER GABOR, ERSZEBET JABLONKAI, ANDRAS VISEGRADI, ZSOLT NEMETHY, JANOS ELES, ISTVAN LEDNECZKI, GYORGY ISTVAN LEVAY, JOZSEF LEVENTE PETRO, GYORGY SELENYI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide modulators of α7 nicotinic acetylcholine receptor activity.SOLUTION: The present invention provides a compound of formula (I) or its pharmaceutically acceptable salt thereof, biologically active metabolite, prodrug, racemate, enantiomer, diastereomer, solvate, or hydrate. Specifically, 5-(3,4-dimethoxyphenyl)-2-methyl-N-(3-methylphenyl)-1,1-dioxo-2H-1λ6,2,6-thiadiazine-3-carboxamide is illustrated.SELECTED DRAWING: None 【課題】α７ニコチン性アセチルコリン受容体活性の調節薬を提供する。【解決手段】下記式（Ｉ）の化合物：TIFF2024056879000087.tif46170またはその薬学的に許容される塩、生物学的に活性な代謝産物、プロドラッグ、ラセミ体、エナチオマー、ジアステレオマー、溶媒和物、もしくは水和物を提供する。具体的には、例えば５－（３，４－ジメトキシフェニル）－２－メチル－Ｎ－（３－メチルフェニル）－１，１－ジオキソ－２Ｈ－１λ６，２，６－チアジアジン－３－カルボキサミドが示される。【選択図】なし