3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONE AS MEK INHIBITOR

To provide a pharmaceutical composition, effective for treating tumors mediated by MEK, including therapies that can target tumors in the CNS by penetrating the blood-brain barrier (BBB) and/or blood-CSF barrier (BCSFB).SOLUTION: The present invention provides a compound of formula (I) or a pharmace...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WESLEY DAVID CLARK, JAMES FRANCIS BLAKE, JENNIFER LYNN FULTON, DAVID AUSTIN MORENO, SIDNIE TAYLER BLANCHET, JOSHUA RYAN DAHLKE, ALLEN SHELLEY, REN LI, ALEX ANDREW KELLUM, PATRICK MICHAEL DOERNER BARBOUR, MARK LAURENCE BOYS, ELLEN MARGARET KNAPP, FAITH ELIZABETH WITKOS, JACOB MATTHEW O'LEARY, CONOR JAMES KAUDORI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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