PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL PREPARATION
To provide a pharmaceutical composition comprising loperamide hydrochloride and turmeric, which enables inhibition of discoloration and improvement of the elution rate.SOLUTION: A pharmaceutical composition comprises component (A): at least one selected from loperamide and pharmaceutically acceptabl...
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| Format: | Patent |
| Sprache: | eng ; jpn |
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| Zusammenfassung: | To provide a pharmaceutical composition comprising loperamide hydrochloride and turmeric, which enables inhibition of discoloration and improvement of the elution rate.SOLUTION: A pharmaceutical composition comprises component (A): at least one selected from loperamide and pharmaceutically acceptable salts thereof, component (B): at least one selected from the group consisting of turmeric and extract thereof, and component (C): at least one selected from silicate comprising at least one metal composed of aluminum or magnesium, and hydrotalcite, wherein the mass ratio represented by component (C)/component (A) is 50-1000.SELECTED DRAWING: None
【課題】ロペラミド塩酸塩とウコンとを含有する医薬組成物において、変色抑制と溶出率向上とを図る。【解決手段】（Ａ）成分：ロペラミド及びその医薬的に許容可能な塩から選ばれる少なくとも１種と、（Ｂ）成分：ウコン及びそのエキスからなる群から選択される少なくとも１種と、（Ｃ）成分：アルミニウム、マグネシウムからなる１種以上の金属を含むケイ酸塩及びヒドロタルサイトから選ばれる１種以上と、を含有し、前記（Ｃ）成分／前記（Ａ）成分で表される質量比は５０～１０００であることよりなる。【選択図】なし |
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