BIOCOMPATIBLE POLYMER COMPOSITION AND APPLICATION THEREOF

To provide a biocompatible polymer composition having excellent handling properties which becomes a protein stabilizer having excellent protein-stabilizing ability, a blocking agent having an excellent sensitizing effect, and a cell culture medium additive capable of culturing an antibody-producing...

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Bibliographische Detailangaben
Hauptverfasser:	TAO FUMIYA, BABA KOKI, KANAI YUUKI, OGIWARA NAOTO, TAKAHASHI MITSUHIRO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC MACROMOLECULAR COMPOUNDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide a biocompatible polymer composition having excellent handling properties which becomes a protein stabilizer having excellent protein-stabilizing ability, a blocking agent having an excellent sensitizing effect, and a cell culture medium additive capable of culturing an antibody-producing cell having excellent antibody productivity and cell activity.SOLUTION: There is provided a biocompatible polymer composition which comprises a vinyl-based polymer (A) having an amine oxide group and a weight average molecular weight of 5000 or more and water and has a surface tension at 25°C of 30 to 50 dyn/cm in a 1% aqueous solution.SELECTED DRAWING: None 【課題】本発明の目的は、タンパク質安定化能に優れたタンパク質安定化剤、増感効果に優れたブロッキング剤、並びに、抗体生産性及び細胞活性に優れた抗体産生細胞を培養能な細胞培養培地添加剤となる、ハンドリング性に優れた生体適合性ポリマー組成物を提供することにある。【解決手段】アミンオキシド基を有し、かつ重量平均分子量が５，０００以上であるビニル系ポリマー（Ａ）及び水を含み、１％水溶液での２５℃における表面張力が３０～５０ｄｙｎ／ｃｍである、生体適合性ポリマー組成物。【選択図】なし