NEW FORMULATION

To provide formulations comprising dipeptidylpeptidase IV (DPP-IV) inhibitors, preferably vildagliptin and metformin, tablets comprising such formulations, and processes for the preparation thereof.SOLUTION: A pharmaceutical composition comprises between 50 to 98 wt.%, between 60 to 98 wt.%, between...

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Bibliographische Detailangaben
Hauptverfasser:	KOWALSKI JAMES, VASANTHAVADA MADHAV, TONG WEI-QIN, JOSHI YATINDRA, LAKSHMAN JAY PARTHIBAN, ROYCE ALAN EDWARD
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide formulations comprising dipeptidylpeptidase IV (DPP-IV) inhibitors, preferably vildagliptin and metformin, tablets comprising such formulations, and processes for the preparation thereof.SOLUTION: A pharmaceutical composition comprises between 50 to 98 wt.%, between 60 to 98 wt.%, between 70 to 98 wt.% or 80 to 98 wt.% on a dry weight basis of active ingredients, wherein the active ingredients comprise vildagliptin and metformin, or in each case a pharmaceutically acceptable salt thereof.SELECTED DRAWING: None 【課題】ジペプチジルペプチダーゼＩＶ(ＤＰＰ－ＩＶ)阻害剤、好ましくはビルダグリプチンおよびメトホルミンを含む製剤、かかる製剤を含む錠剤およびそれの製造のための方法を提供する。【解決手段】活性成分がビルダグリプチンおよびメトホルミンまたは各々の場合のその薬学的に許容される塩からなり、乾燥重量に基づいて５０から９８重量％の間、６０から９８重量％の間、７０から９８重量％または８０から９８重量％の間の活性成分を含む医薬組成物とする。【選択図】なし