SITAGLIPTIN-CONTAINING TABLET

To provide a sitagliptin phosphate tablet having improved chemical stability.SOLUTION: A tablet contains sitagliptin, a pharmacologically acceptable salt thereof, or a hydrate thereof, and one or more lubricants selected from the group consisting of stearic acid, sodium stearyl fumarate, sucrose fat...

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Bibliographische Detailangaben
Hauptverfasser:	ZAIKE SHINNOSUKE, SUGAWARA YUKI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a sitagliptin phosphate tablet having improved chemical stability.SOLUTION: A tablet contains sitagliptin, a pharmacologically acceptable salt thereof, or a hydrate thereof, and one or more lubricants selected from the group consisting of stearic acid, sodium stearyl fumarate, sucrose fatty acid ester, hardened oil, and talc.SELECTED DRAWING: None 【課題】化学的に安定性を向上させたシタグリプチンリン酸塩錠を提供することを目的とする。【解決手段】シタグリプチン、その薬理上許容される塩、又はそれらの水和物と、ステアリン酸、フマル酸ステアリルナトリウム、ショ糖脂肪酸エステル、硬化油、及びタルクからなる群より選択される１種または２種以上の滑沢剤とを含有してなる、錠剤を提供する。【選択図】なし