COATING FOR INTRALUMINAL EXPANDABLE CATHETER PROVIDING CONTACT TRANSFER OF DRUG MICRO-RESERVOIRS

To provide a coating for an intraluminal expandable catheter providing contact transfer of drug micro-reservoirs.SOLUTION: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurali...

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Bibliographische Detailangaben
Hauptverfasser:	JOHN EDWIN SHULZE, ROBERT JOHN ELICKER, RONALD KENICHI YAMAMOTO, MICHAEL THOMAS AHLERING, NGUYEN TIEN THUY, JELLE JURJEN ZOETHOUT
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a coating for an intraluminal expandable catheter providing contact transfer of drug micro-reservoirs.SOLUTION: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.SELECTED DRAWING: Figure 1 【課題】薬物マイクロリザーバの接触移動を提供する管腔内拡張型カテーテル用コーティングを提供すること。【解決手段】親油性マトリックスと、親油性マトリックスに分散した複数のマイクロリザーバとを備えるカテーテルの膨張可能部位のコーティングを開示する。複数のマイクロリザーバは活性剤を含む。また、コーティング製剤およびコーティングを形成する方法も開示する。さらに、膨張可能部位上のコーティングを備えるカテーテルと、病態を治療する方法も提供される。【選択図】図１