METHOD FOR IMPROVING CARDIAC MUSCLE PERFORMANCE IN FONTAN PATIENT BY USING UDENAFIL COMPOSITION

To provide udenafil or a pharmaceutically acceptable salt thereof for an improved therapy related to complication or adverse effect in a patient who received a fontan operation.SOLUTION: Provided is a pharmaceutical composition containing udenafil or a pharmaceutically acceptable salt thereof for us...

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Bibliographische Detailangaben
1. Verfasser:	JAMES L YEAGER
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide udenafil or a pharmaceutically acceptable salt thereof for an improved therapy related to complication or adverse effect in a patient who received a fontan operation.SOLUTION: Provided is a pharmaceutical composition containing udenafil or a pharmaceutically acceptable salt thereof for use in improving athletic ability determined by VO2 improvement in maximum effort or in a ventilatory anaerobic threshold (VAT) in a patient having fontan physiology, where a dosage of udenafil or the pharmaceutically acceptable salt thereof is 87.5 mg, and the composition is administered twice a day.SELECTED DRAWING: None 【課題】フォンタン術を受けた患者において、合併症又は副作用に関連する改良治療法のためのウデナフィル又はその薬剤的に許容可能な塩を提供する。【解決手段】フォンタン生理を有する患者において、最大努力時または換気無酸素性閾値（ＶＡＴ）におけるＶＯ２の改善によって決定される運動能力の改善の用途のためのウデナフィル又はその薬剤的に許容可能な塩を含有する医薬組成物であって、ウデナフィル又はその薬剤的に許容可能な塩の投与量が８７．５ｍｇであり、前記組成物が１日２回投与される医薬組成物を提供する。【選択図】なし