R2R1/2 IN DIAGNOSIS AND THERAPY

To provide compounds and methods for use in the treatment of cardiac and pulmonary diseases as well as cancer.SOLUTION: The present invention provides a polynucleotide comprising the R2R1/2 gene, for use in treating one or more diseases and/or conditions selected from the group consisting of: (a) ca...

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Hauptverfasser: PEETERS PIETER JOHAN, JEROEN MARCEL MARIA ROGER AERSSENS, RONALD ANTHONIUS DE HOOGT, VAN BREMPT RONALD KAREL LOUISA, MARCUS CORNELIS DE RUITER
Format: Patent
Sprache:eng ; jpn
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Beschreibung
Zusammenfassung:To provide compounds and methods for use in the treatment of cardiac and pulmonary diseases as well as cancer.SOLUTION: The present invention provides a polynucleotide comprising the R2R1/2 gene, for use in treating one or more diseases and/or conditions selected from the group consisting of: (a) cardiac diseases and/or conditions; (b) pulmonary diseases and/or conditions.; and (c) cancer, wherein the R2R1/2 gene comprises a sequence selected from the group consisting of a plurality of specific sequences, or a sequence at least 60% identical thereto.SELECTED DRAWING: None 【課題】本発明は、心臓および肺疾患ならびに癌の治療に使用するための化合物および方法を提供する。【解決手段】(a)心疾患および/または状態;(b)肺疾患および/または状態;ならびに(c)癌;からなる群から選択される1以上の疾患および/または状態の治療に使用するための、R2R1/2遺伝子を含むポリヌクレオチドであって、R2R1/2遺伝子が、複数の特定の配列からなる群から選択される配列またはそれらと少なくとも60%同一の配列を有する前記ポリヌクレオチド。【選択図】なし