PHARMACEUTICAL COMPOSITION

To provide a compound for treating and preventing diseases and conditions including heart failure, heart failure with a maintained ejection fraction, heart failure with a mildly reduced ejection fraction, heart failure with a reduced ejection fraction, chronic kidney disease, and acute kidney injury...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HANS FREDRIK BERGSTROEM, HENRIK GRADEN, STIG JONAS BOSTROEM, LARS JOHAN ANDREAS ULANDER, NIWA YASUNARI, GIULIA BERGONZINI, SAKAMAKI SHIGEKI, KENNETH LARS GRANBERG, FUCHIGAMI RYUICHI, FUJIO MASAKAZU
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a compound for treating and preventing diseases and conditions including heart failure, heart failure with a maintained ejection fraction, heart failure with a mildly reduced ejection fraction, heart failure with a reduced ejection fraction, chronic kidney disease, and acute kidney injury.SOLUTION: The present invention provides a compound represented by formula (I) or its pharmaceutically acceptable salt. Such a compound is RXFP1 modulator and is useful as a treatment agent.SELECTED DRAWING: None 【課題】心不全、駆出率が保たれた心不全、駆出率が軽度低下した心不全、駆出率が低下した心不全、慢性腎疾患及び急性腎損傷を含む疾患及び状態の処置及び予防のための化合物を提供する。【解決手段】式（Ｉ）で示される化合物又はその薬学的に許容し得る塩である。そのような化合物は、ＲＸＦＰ１モデュレーターであり、治療剤として有用であり得る。TIFF2023179389001042.tif62169【選択図】なし